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KMID : 1103720110640010091
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Journal of the Korean Society of Radiology
2011 Volume.64 No. 1 p.91 ~ p.95
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KIT-negative Gastrointestinal Stromal Tumor in a Child: A Case Report
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Lim Se-Woong
Lee Young-Hwan
Park Sang-Hyun
Choi Du-Young
Choi Keum-Ha
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Abstract
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We report here on the imaging findings of the case of KIT-negative gastrointestinal stromal tumor (GIST) in the stomach of a 12-year-old girl. Radiologic studies revealed the presence of a huge exophytic growing mass that originated from the gastric wall and this mass consisted of solid and cystic components on USG, CT and MR. The cystic regions were mainly located at the periphery of the mass and they were revealed to be myxoid degeneration and hemorrhage on histopathologic examination. The tumor consisted of epithelioid and typical spindle cells and they showed negative immunoreactivity for KIT. Although KIT-negative GISTs are rare, they can be considered in the differential diagnosis when a large heterogeneous extraluminal mass that contains solid portions and various degrees of peripheral cystic regions is observed.
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KEYWORD
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Gastrointestinal Stromal Tumor, Proto-Oncogene Protein, c-kit, Child
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